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Fighting Swine Flu through Computational Medicine

Presenter:
Klaus Schulten  (University of Illinois at Urbana-Champaign)
Masterworks Session
Multi-Scale Simulations in Bioscience
Wednesday,  04:15PM - 05:00PM
Room PB253-254
Abstract:
The swine flu virus, spreading more and more rapidly, threatens to also become resistant against present forms of treatment. This lecture illustrates how a look through the "computational microscope" (CM) contributes to shaping a pharmacological strategy against a drug resistant swine flu. The CM is based on simulation software running efficiently on many thousands of processors, analyzes terabytes of data made available through GPU acceleration, and is adopted in the form of robust software by thousands of biomedical researchers worldwide. The swine flu case shows the CM at work: what type of computing demands arise, how software is actually deployed, and what insight emerges from atomic resolution CM images. In viewing, in chemical detail, the recent evolution of the swine flu virus against the binding of modern drugs, computing technology responds to a global 911 call.
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